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The life expectancy of the Norwich Terrier is 12-16 years. While the Norwich Terrier is considered a healthy breed, there are some health issues for which responsible breeders do preventative genetic health testing, thereby reducing the incidences. For the Norwich, there are instances of epilepsy, narrow tracheas, luxating patellas, hip dysplasia, mitral valve disease, and incorrect bites (how the teeth meet when the jaws are closed).

Like all dogs, Norwich Terriers can have autoimmune reactivity to rabies vaccinations. Rabies-Vaccine-Induced Ischemic Dermatopathy, or RVI-ID, is a non-fatal but potentially serious reaction to chemicals called adjuvants in the vaccine. RVI-ID is often misdiagnosed, but if correctly diagnosed, is treatable. Symptoms may include: symmetrical dark spots or lesions at the tips of the ears; swelling, hard lumps or dark spots in the vicinity of the injection site.

Norwich owners are seeing more dogs with breathing concerns, and the Norwich and Norfolk Terrier Club (USA) has formed a new "Health and Genetics Sub-Committee for Research on Upper Airway Syndrome in Norwich Terriers" (source: "The Norwich & Norfolk News," Number 93, Fall 2006). Upper Airway Syndrome (UAS) covers all abnormalities that can occur in the upper airway, including: elongated soft palates; too short soft palates; narrow/misshapen tracheas; collapsing tracheas; stenotic nares (nasal passages that are too small); swollen tonsils; everted laryngeal saccules. These upper airway disorders can occur singly or in combination with one or two others. All compromise the airway and the dog's ability to breathe normally; the dog's breathing often sounds raspy or moist. It may be that shorter muzzles may have increased incidence of such issues. Reputable breeders are aware of these issues, and are working assiduously to protect the breed.